ALICE is the new university-wide HPC cluster that is currently in development. In addition to research, Alice can also be used for courses and by students. Currently ALICEdoes not yet support all the features that Shark does (e.g.: hardware accelerated graphics), however implementation of these is planned for the near future. We would advice potential HPC users (who are not working on the LUMC Shark cluster already) to start on ALICE right away, so that a switch later on will not be necessary.


General information:  The best source of information on ALICE is the official ALICE Wiki.

FSW specific issues:  For FSW specific topics, i.e. fMRI analysis, Matlab usage, data-transfer etc, we will provide additional information on the page below.

Accounts & Contact: for all questions about ALICE usage and accounts please contact SOLO:, only for password reset contact ALICE admin directly:


To use FSL on the ALICE cluster, do not use the default FSL module. Instead load the following (in order):

  • module load Mesa/20.0.2-GCCcore-9.3.0
  • module load LUMC
  • module load neuroImaging/fsl/6.0.4


fMRIprep is a pipeline of fMRI processing tools that allows for highly reproducible analyses. Usage of fMRIPrep on ALICE is possible using Singularity containers. Please note that Singularity itself is just a container technology, and you still need an fMRIPrep image.

Available versions

There are two standard fMRIPrep images already on ALICE that you can use. You can find them in:


To use them, first load the Singularity module (for the default version use):

module load Singularity

Then run one of the singularity images and specify the required paths. Note that if you want to read/write data to either /data1/ or /scratchspace/ folders these need to be mounted explicitly to the container (Home is mounted by default), e.g.

$ singularity run --cleanenv -B /data1/path_to_your_folder,/scratchdata/path_to_your_folder  /cm/shared/singularity_images/f/fmriprep-20.2.3.simg \
    path/to/data/dir path/to/output/dir \
    participant \
    --participant-label label

For pointers on how to run fMRIPrep with SLURM sbatch scripts, please see here.


The use of freesurfer in fMRIprep requires a freesurfer license, the path to this license needs to be specified in the singularity call.

Custom containers

Alternatively, you can download an image to your home folder and use that (follow the instructions here). Keep in mind that fMRIPrep may not be specifically optimized for the SLURM scheduler on ALICE and may either need custom adjustments or may submit jobs in a sub-optimal way.


SPM software package for Matlab allows for the analysis of brain imaging data sequences. For now, SPM is not offered on ALICE as a module, instead you can install it yourself in your home directory. See here for information on installing SPM.


MRIcron is a cross-platform NIfTI format image viewer. You can download it to your home directory. To use it, we recommand using X2Go to connect to ALICE.


For instruction on how to use X2Go with ALICE see here.

Known issues:

  • Copy-Paste from local to remote: sometimes the copy-paste functionality from the local machine to the X2Go client stops working. In most cases this is fixed by copy-pasting some text on the remote machine, e.g.: in a terminal or text-editor on the X2Go client copy and then paste some text. Afterward, the copy-paste from the local machine should work again.